NeuroFramework 3D-sMRI | Research Workstation

Research Cohort

ABIDE-I

Select a Verified Benchmark Scan:

Web preview includes 9 multi-site benchmark subjects. To run live neural processing on custom NIfTI scans, refer to the NeuroFramework-ai repository ↗.

Note: Demographics are strictly for PDF documentation and do not alter AI inference.

Age (Years)

Sex

Scanner Facility

Processing Pipeline

Idle

Scan Ingestion & Validation Header parsing & voxel dimension check

Otsu Brain Masking Adaptive scalp and skull fat stripping

N4 Bias Correction Magnetic field shading homogenization

Crop & Z-Score Normalization Site-harmonized percentile clipping

50-Slice Multi-Planar Extract Axial, Coronal, Sagittal @ 224x224 HD

Conv3D-CBAM Inference Multi-stream feature fusion & attention

PRE-PROCESSING BASELINE

Original / Raw Input MRI Scan

Awaiting Scan Selection Scalp & Cranium Intact

🧠 No Scan Loaded Select a preloaded ABIDE-I research subject on the left panel to inspect the unstripped anatomical baseline and launch tri-planar analysis.

Source Plane Axial Acquisition (Center Slice)

Modality T1-Weighted 3D-sMRI

Cranial State Non-Brain Tissues Present

Intensity Calibration Native Scanner Dynamic Range

Voxel Resolution 1.0 mm Isotropic (Raw Mesh)

Volume Format NIfTI-1 Header Verified

Axial (Z) Horizontal Plane

Slice: 25 / 50

🔬 Awaiting Scan Ingestion

Coronal (Y) Frontal Plane

Slice: 25 / 50

🔬 Awaiting Scan Ingestion

Sagittal (X) Midline Profile

Slice: 25 / 50

🔬 Awaiting Scan Ingestion

Research Classification

Model Output

--.-% ASD Probability

Awaiting Input Latency: -- ms

Multi-View Feature Analysis

L2 Norms

Measures the relative representation strength across the three anatomical streams:

Axial Stream --%

Coronal Stream --%

Sagittal Stream --%

Preprocessing Audit

QC Checklist

○ Otsu Brain Masking
○ N4 Bias Homogenization
○ Bounding Box Alignment
○ Site-Harmonized Z-Score
○ 50-Slice Multi-Planar Tensors

Anatomical Stream	Feature Vector Dimension	L2 Activation Norm	Relative Share (%)	Target Biomarker Structures
Axial (Horizontal)	256-dim	0.24	38.2%	Prefrontal cortex, superior temporal sulcus
Coronal (Frontal)	256-dim	0.19	29.4%	Amygdala-hippocampal complex, lateral ventricles
Sagittal (Profile)	256-dim	0.21	32.4%	Corpus callosum hypoplasia, cerebellar vermis VI-VII

Cohort / Protocol	Resolution	Peak Fold	5-Fold Average
Multi-Site (NYU + UM_1 + USM)	50 Slices @ 224x224 HD	75.95% (Fold 1)	66.84%
Single-Site (NYU Alone, N=184)	50 Slices @ 128x128	75.00%	69.59%

Original / Raw Input MRI Scan

Clinical AI Neuroimaging Report

1. DEEP LEARNING CLASSIFICATION FINDINGS

2. TRI-PLANAR VOLUMETRIC SLICE CAPTURES (CENTER PLANES)

3. MULTI-VIEW FEATURE REPRESENTATION ANALYSIS (L2 NORMS)

4. PREPROCESSING PIPELINE INTEGRITY AUDIT

5. RESEARCH IMPRESSION & METHODOLOGICAL NOTES

Architecture & Benchmark Specifications

Web Preview vs. Full Application Architecture

Peer-Reviewed Reference

Multi-Site Validation Benchmarks (ABIDE-I, N=395)

Architectural Mechanics